The SNR gain is also a function of spectrum sparsity, and the best results are obtained for spectra with very few, strong mass peaks
P.S 2: This blog entry was triggered by a discussion with Sujithra Raviselvam on the Google+ group and stemmed from a 2005 blog entry which featured the thesis of Earle Stone 
Zare Lab, HADAMARD TRANSFORM TIME-OF-FLIGHT MASS SPECTROMETRY by Matthew Robbins, Griffin Barbula, Richard Perry
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