Friday, March 16, 2012

Next-Generation Sequencing Technologies Videos

It's Friday, here are some of the videos that might get you thinking following up on the videos presented a while back. It might perhaps give a new perspective to our current awful inabilities.

Next-Generation Sequencing Technologies by Elaine Mardis (2012). More videos and presentations from that meeting can be found here. The slides of the presentation are here.

by Elliott H. Margulies

 Two slides got my attention out of many other intriguing ones: From  Mardis' presentation, this one slide with what she says is nothing short of an extraordinary story (see the written text underneath the image below):

In short, chemotherapy brings a good news/bad news story for small cell cancer (a certain type of Lung cancer). The good news is that chemotherapy will fix it within two to three weeks but the bad news is that, in six months, it will kill you. Or at least this was the prognosis two years ago, chemo has certainly improved. I just find it amazing that we are able to find out exactly what clone survived and changed because of the chemo and how it eventually takes over. Talk about personalized medicine....

From Margulies' presentation, it looks like genomics is now going to have to work on entire populations (as opposed to just one person) and methods like those featured in Compressed Se(que)nsing or Compressed Sensing Approach for High Throughput Carrier Screen might help there as well:

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